Search on: CASEIN KINASES 
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Descriptor English:   Casein Kinases 
Descriptor Spanish:   Caseína Quinasas 
Descriptor Portuguese:   Caseína Quinases 
Synonyms English:   Casein Kinase  
Tree Number:   D08.811.913.696.620.682.700.140
D12.644.360.150
D12.776.476.150
Definition English:   A group of protein-serine-threonine kinases that was originally identified as being responsible for the PHOSPHORYLATION of CASEINS. They are ubiquitous enzymes that have a preference for acidic proteins. Casein kinases play a role in SIGNAL TRANSDUCTION by phosphorylating a variety of regulatory cytoplasmic and regulatory nuclear proteins. 
Indexing Annotation English:   general or unspecified; prefer specifics
History Note English:   2005(1974) 
Allowable Qualifiers English:  
administration & dosage adverse effects
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   38707 
Unique Identifier:   D047388 

Occurrence in VHL: 		 

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